Infiltrating the largest organ of the human body and reaching its deep dermal layers is key to stimulating the renewal of cells. Many attempts have been made, but the results have been disappointing due to poor formulation and poor vitamin stability. Scientists at Inter-Cal set out to prove that Ester-C^® Topical could reach down to deep layers of the skin where collagen and other important support structures are produced. In an independent test, Ester-C^® Topical (14% vitamin C) and a cream containing 1% Ester-C^® Topical were applied in a randomized pattern to eight sites on the skin of the inside forearms of five subjects. The test showed that vitamin C from both  were able to penetrate the skin barrier to access the cells and tissues involved in the maintenance and repair of skin.

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